File:Lambda life cyl..jpg

The λ Life Cycle and Gene Organization

(A) The lytic compared to the lysogenic life cycle. Invading phage can either replicate and lyse the host cell (1), or they can integrate into the host genome (2) where they replicate as part of the host genome. At a frequency of approximately 10−6 to 10−5 per cell division, the prophage escapes cI repression, replicates, and lyses the host (3)

(B) The genetic map showing the approximate organization of functional blocks and, below the map, the location of the genes up and down regulated as revealed in this study. The lom gene is embedded between two different tail-fiber genes. The genome length is 48.5 kb, approximately 75 genes. See [2,29].

From: Population Fitness and the Regulation of Escherichia coli Genes by Bacterial Viruses Chen Y, Golding I, Sawai S, Guo L, Cox EC PLoS Biology Vol. 3, No. 7, e229 doi:10.1371/journal.pbio.0030229

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