Mephenytoin: Difference between revisions

From Citizendium
Jump to navigation Jump to search
imported>David E. Volk
No edit summary
imported>David E. Volk
Line 24: Line 24:
== Synonyms and brand names ==
== Synonyms and brand names ==
===Synonyms===
===Synonyms===
Mephentoin  
*Mephentoin  
Methyl Hydantoin  
*Methyl Hydantoin  
Methylphenetoin  
*Methylphenetoin  
   
   
===Brand Names ===
===Brand Names ===
Epiazin®  
*Epiazin®  
Gerot-Epilan®  
*Gerot-Epilan®  
Insulton®  
*Insulton®  
Mesdontoin®  
*Mesdontoin®  
Mesontoin®  
*Mesontoin®  
Methoin®  
*Methoin®  
Metydan®  
*Metydan®  
Phenantoin®  
*Phenantoin®  
Sacerno®  
*Sacerno®  
Sedantional®  
*Sedantional®  
Sedantoin®  
*Sedantoin®  
Sedantoinal®  
*Sedantoinal®  
Triantoin®  
*Triantoin®
 
== External links ==
== External links ==
{{DailyMed}}
{{DailyMed}}

Revision as of 07:39, 25 June 2008

This article is a stub and thus not approved.
Main Article
Discussion
Related Articles  [?]
Bibliography  [?]
External Links  [?]
Citable Version  [?]
 
This editable Main Article is under development and subject to a disclaimer.
Mephenytoin.jpg
mephenytoin
IUPAC name: 5-ethyl-3-methyl-5-phenylimidazolidine-2,4-dione
Synonyms: mephentoin, methyl hydantoin, methylphenetoin
Formula: C12H14N2O2

 Uses: anti-seizure drug

 Properties:

 Hazards:

Mass (g/mol): CAS #:
218.2518 50-12-4


Mephenytoin (Mesantoin®) is an anticonvulsant medication used to treat epilepsy and it is particularly effective in tonic-clonic epilepsy . Its common chemical name is 3-methyl 5,5-phenyl-ethyl-hydantoin and its IUPAC chemical name is 5-ethyl-3-methyl-5-phenylimidazolidine-2,4-dione. It has pharmacological effects similar to phenytoin and the barbiturates.

Mechanism of action

The mechanism of action of mephenytoin is not definitely known, but extensive research strongly suggests that its main mechanism is to block frequency-, use- and voltage-dependent neuronal sodium channels, and therefore limit repetitive firing of action potentials.[1]


Synonyms and brand names

Synonyms

  • Mephentoin
  • Methyl Hydantoin
  • Methylphenetoin

Brand Names

  • Epiazin®
  • Gerot-Epilan®
  • Insulton®
  • Mesdontoin®
  • Mesontoin®
  • Methoin®
  • Metydan®
  • Phenantoin®
  • Sacerno®
  • Sedantional®
  • Sedantoin®
  • Sedantoinal®
  • Triantoin®

External links

Mephenytoin - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine). Template:MedMaster Template:DrugBank

References

  1. DrugBank page for Mephenytoin. Retrieved on 062508.